Selected Publications

Kreisel D, Gelman AE, Higashikubo R, Lin X, Vikis HG, White JM, Toth KA,  Deshpande C, Carreno BM, You M, Taffner SM, Yokoyama W, Bui JD,  Schreiber RD, Krupnick AS.  Strain-Specific Variation in Murine Natural Killer  Gene Complex Contributes to Differences in Immunosurveillance for Urethane-Induced Lung Cancer. Cancer Research 2012 Jun 29. [Epub ahead of print] PMID: 22751136
Li W, Nava RG, Bribriesco AC, Zinselmeyer BH, Spahn JH, Gelman AE, Krupnick AS,  Miller MJ, Kreisel D. Intravital 2-photon imaging of leukocyte trafficking in  beating heart. J Clin Invest. 2012 Jun 18. pii: 62970. doi: 10.1172/JCI62970. [Epub ahead of print] PMID: 22706307

Li W, Bribriesco AC, Nava RG, Brescia AA, Ibricevic A, Spahn JH, Brody SL, Ritter JH, Gelman AE, Krupnick AS, Miller MJ, Kreisel D. Lung transplant acceptance  is facilitated by early events in the graft and is associated with lymphoid  neogenesis. Mucosal Immunol. 2012 May 2. . PMID: 22549742

Krupnick AS, Tidwell VK, Engelbach JA, Gelman, AE, Kreisel D, Alli, V, Nehorai A, You M, Vikis H, Garbow J. Quantitative monitoring of murine lung tumors by magnetic resonance imaging. Nature Protocols.  Jan 2012 5;7(1):128-42. doi: 10.1038/nprot.2011.424. PMID: 22222788

Boomer J, To K , Chang K, Takasu O, Osborne D, Walton A , Bricker T, Jarman S, Kreisel D, Krupnick AS, Srivastava A, Swanson P, Green J, Hotchkiss R.  Immunosuppression in Patients Dying of Sepsis and Multiple Organ Failure.  JAMA: Journal of the American Medical Association. 2011 Dec 21;306(23):2594-605. PMID: 22187279

Vikis HG, Gelman AE, Franklin A, Stein L, Rymaszewski A, Zhu J, Liu P, Tichelaar JW, Krupnick AS, You M. Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis. Molecular Carcinigenesis. 2011 Oct 17. doi: 10.1002/mc.20870. [Epub ahead of print] PMID: 22006501

Kreisel D, Sugimoto S, Zhu J, Nava R, Li W, Okazaki M, Yamamoto S, Ibrahim M, Huang HJ, Toth KA, Ritter JH, Krupnick AS, Miller MJ, Gelman AE  Emergency granulopoiesis promotes neutrophil-dendritic cell encounters that prevent mouse lung allograft acceptance. Blood 2011 Oct 5. [Epub ahead of print]  PMID: 21972291

Tidwell VK, Garbow JR, Krupnick AS, Engelbach JA, Nehorai A. Quantitative analysis of tumor burden in mouse lung via MRI.  Magnetic Resonance in Medicine.  2011 Sep 27 PMID: 21954021

Huang HJ, Sugimoto S, Lai J, Okazaki M, Yamamoto S, Krupnick AS, Kreisel D, Gelman AE. Maintenance of IKKβ Activity Is Necessary to Protect Lung Grafts From Acute Injury. Transplantation. 2011 Feb 2

Kreisel D, Sugimoto S, Tietjens J, Zhu J, Yamamoto S, Krupnick AS, Carmody RJ, Gelman AE. Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis. J Clin Invest. 2010 Dec 13. [Epub ahead of print] PMID: 21157041

Kreisel D, Krupnick AS, Puri V, Guthrie TJ, Trulock EP, Meyers BF, Patterson GA. Short- and long-term outcomes of 1000 adult lung transplant recipients at a single center. J Thorac Cardiovasc Surg. 2010 Nov 18. [Epub ahead of print] PMID: 21093882

Kreisel D, Nava RG, Li W, Zinselmeyer BH, Wang B, Lai J, Pless R, Gelman AE, Krupnick AS, Miller MJ. In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation. Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18073-8 PMID: 20923880

Kreisel D, Lai J, Richardson SB, Ibricevic A, Nava RG, Lin X, Li W, Kornfeld CG,Miller MJ, Brody SL, Gelman AE, Krupnick AS. Polarized Alloantigen Presentation by Airway Epithelial Cells Contributes to Direct CD8+ T Cell Activation in the Airway. Am J Respir Cell Mol Biol. 2010 Sep 20. [Epub ahead of print] PMID: 20855651

Kreisel D, Richardson SB, Li W, Lin X, Kornfeld CG, Sugimoto S, Hsieh CS, Gelman AE, Krupnick AS. Cutting edge: MHC class II expression by pulmonary nonhematopoietic cells plays a critical role in controlling local inflammatory responses. J Immunol. 2010 Oct 1;185(7):3809-1.

Nava RG, Li W, Gelman AE, Krupnick AS, Miller MJ, Kreisel D. Two-photon microscopy in pulmonary research Semin Immunopathol. 2010 Sep;32(3):297-304.

Murala S, Alli V, Kreisel D, Gelman AE, Krupnick AS. Current Status of Immunotherapy for the Treatment of Non-Small Cell Lung Cancer. Journal of Thoracic Disease. 2010 Dec; 2: 237-244..

Vikis HG, Jackson EN, Krupnick AS, Franklin A, Gelman AE, Chen Q, Piwnica-Worms D, You M. Strain-Specific Susceptibility for Pulmonary Metastasis of Sarcoma 180 Cells in Inbred Mice. Cancer Res. 2010 May 25. [Epub ahead of print]

Gelman AE, Okazaki M, Sugimoto S, Li W, Kornfeld CG, Lai J, Richardson SB, Kreisel FH, Huang HJ, Tietjens JR, Zinselmeyer BH, Patterson GA, Miller MJ, Krupnick AS, Kreisel D. CCR2 regulates monocyte recruitment as well as CD4 T1 allorecognition after lung transplantation. Am J Transplant. 2010 May;10(5):1189-99.

Puri V, Garg N, Engelhardt EE, Kreisel D, Crabtree TD, Meyers BF, Patterson GA, Krupnick AS. Tumor location is not an independent prognostic factor in early stage non-small cell lung cancer. Annals of Thoracic Surgery. 2010 Apr;89(4):1053-9.

Li W, Sugimoto S, Lai J, Patterson GA, Gelman AE, Krupnick AS, Kreisel D. Orthotopic vascularized right lung transplantation in the mouse. Journal of Thoracic and Cardiovascular Surgery. 2010 Jun;139(6):1637-43.

Sugimoto S, Lin X, Lai J, Okazaki M, Das NA, Li W, Krupnick AS, Chen R, Jeong SS, Patterson GA, Kreisel D, Gelman AE. Apyrase treatment prevents ischemia-reperfusion injury in rat lung isografts. Journal of Thoracic and Cardiovascular Surgery 2009 Sep;138(3):752-9. Epub 2009 Jul 10

Gelman AE, Li W, Richardson SB, Zinselmeyer BH, Lai J, Okazaki M, Kornfeld CG, Kreisel FH, Sugimoto S, Tietjens JR, Dempster J, Patterson GA, Krupnick AS, Miller MJ, Kreisel D. Cutting edge: Acute lung allograft rejection is independent of secondary lymphoid organs.  Journal of Immunology 2009 Apr 1;182(7):3969-73

Krupnick AS, Lin X, Li W, Okazaki O, Lai M, Sugimoto S, Richardson SB, Kornfeld CG, Garbow JR, Patterson GA, Gelman AE, Kreisel D. Orthotopic Mouse Lung Transplantation as Experimental Methodology to Study Transplant and Tumor Biology. Nature Protocols. 2009; 4(1):86-93

Krupnick AS, Gelman AE, Okazaki M, Lai J, Das N, Sugimoto S, Tung TH, Richardson SB, Patterson GA, Kreisel D. The feasibility of diaphragmatic transplantation as potential therapy for treatment of respiratory failure associated with Duchenne muscular dystrophy: acute canine model. Journal of Thoracic and Cardiovascular Surgery. 2008 Jun;135(6):1398-9.

Gelman AE, Okazaki M, Lai J, Kornfeld CG, Kreisel FH, Richardson SB, Sugimoto S, Tietjens JR, Patterson GA, Krupnick AS, Kreisel D.CD4+ T Lymphocytes Are Not Necessary for the Acute Rejection of Vascularized Mouse Lung Transplants. J Immunol. 2008 Apr 1;180(7):4754-62.

Okazaki M, Gelman AE, Tietjens JR, Ibricevic A, Kornfeld CG, Huang HJ, Richardson SB, Lai J, Garbow JR, Patterson GA, Krupnick AS, Brody SL, Kreisel D. Maintenance of airway epithelium in acutely rejected orthotopic vascularized mouse lung transplants. Am J Respir Cell Mol Biol. 2007 Dec;37(6):625-30. 2007 Aug 23.

Okazaki M, Krupnick AS, Kornfeld CG, Lai JM, Ritter JH, Richardson SB, Huang HJ, Das NA, Patterson GA, Gelman AE, Kreisel D. A mouse model of orthotopic vascularized aerated lung transplantation. Am J Transplant. 2007 Jun;7(6):1672-9.

Okazaki M, Kreisel F, Richardson SB, Kreisel D, Krupnick AS, Patterson GA, Gelman AE. Sphingosine 1-phosphate inhibits ischemia reperfusion injury following experimental lung transplantation. Am J Transplant. 2007 Apr;7(4):751-8.

Gelman AE, LaRosa DF, Zhang J, Walsh PT, Choi Y, Sunyer JO, Turka LA.  The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation. Immunity. 2006 Nov;25(5):783-93.

Krupnick AS, Gelman AE, Barchet W, Richardson S, Kreisel FH, Turka LA, Colonna M, Patterson GA, Kreisel D.  Murine vascular endothelium activates and induces the generation of allogeneic CD4+25+Foxp3+ regulatory T cells.  J Immunol. 2005 Nov 15;175(10):6265-70.

Krupnick AS, Balsara KR, Kreisel D, Riha M, Gelman AE, Estives MS, Amin KM, Rosengard BR, Flake AW. Fetal liver as a source of autologous progenitor cells for perinatal tissue engineering. Tissue Eng. 2004 May-Jun;10(5-6):723-35.

Kreisel D, Krasinskas AM, Krupnick AS, Gelman AE, Balsara KR, Popma SH, Riha M, Rosengard AM, Turka LA, Rosengard BR.  Vascular endothelium does not activate CD4+ direct allorecognition in graft rejection.  J Immunol. 2004 Sep 1;173(5):3027-34.

Gelman AE, Zhang J, Choi Y, Turka LA Toll-like receptor ligands directly promote activated CD4+ T cell survival. J Immunol. 2004 May 15;172(10):6065-73.

Krupnick AS, Zhu J, Nguyen T, Kreisel D, Balsara KR, Lankford EB, Clark CC, Levine S, Stedman HH, Shrager JB Inspiratory loading does not accelerate dystrophy in mdx mouse diaphragm: implications for regenerative therapy J Appl Physiol. 2003 Feb;94(2):411-9.

Kreisel D, Krupnick AS, Gelman AE, Engels FH, Popma SH, Krasinskas AM, Balsara KR, Szeto WY, Turka LA, Rosengard BR. Non-hematopoietic allograft cells directly activate CD8+ T cells and trigger acute rejection: an alternative mechanism of allorecognition  Nat Med. 2002 Mar;8(3):233-9

Kreisel D, Krupnick AS, Balsara KR, Riha M, Gelman AE, Popma SH, Szeto WY, Turka LA, Rosengard BR. Mouse vascular endothelium activates CD8+ T lymphocytes in a B7-dependent fashion  J Immunol. 2002 Dec 1;169(11):6154-61.